OAT test review

[Lorraine Love]

Hi
another OAT test for your insights.
Thanks
Lorraine

[DrWoeller]

Lorraine,
I am looking at an OAT with the accession number #427871. I hope this assessment answers your questions – Dr. Woeller:

1 – mild Arabinose value (candida)
2 – all other clostridia and yeast markers normal
3 – oxalate values normal
4 – no mitochondrial imbalances seen
5 – VERY low HVA and VMA linked to dopamine and norepinephrine production, respectively. Also, the 5-HIAA is low too linked to serotonin.

Discussion: this could be a situation of poor protein absorption, consumption or both. H. pylori could lead to protein digestion, SIBO could as well. Low intake may cause it too. There is always the possibility of methylenetetrahydrofolate reductase deficiency (MTHFR A1298C) that compromised folate metabolism along with a tetrahydrobiopterin (BH4) deficiency which compromises various converting enzymes that support dopamine, norepinephrine and serotonin production. I doubt this is occurring because the phenyllactic and phenylpyruvic are both normal on the OAT (which are both linked to phenylalanine metabolism problems).

6 – #42 and #42 can both be high with malnutrition and maldigestion.
7 – Ascorbic acid is likely from supplements or foods – which is fine, its not a problem.
8 – High B5 may be from supplements too
9 – NAC (N-acetyl-cysteine) is low normal. This can contribute to lack of oxidation protection.
10 – 2-hydroxybutyric – seeing this more and more with environmental chemical exposure. This might be the case with this patient? The level is not significantly high though.
11 – amino acid metabolites and phosphoric acid appear fine

Sincerely,
Dr. Woeller

[Lorraine Love]

would you treat mild candida? I think yes in this case because of symptoms –
I had suspected mold/fungus due to environmental work exposure (past) but OAT doesnt show that only mild candida so I can assume ruled out?
she had a NT test done which shows low serotonin, low dopamine, low epinephrine, low glutamate, I am attaching that test as not sure how to coordinate them.
Plan – Biocidin Cleanse, support neurotransmitters by supporting gut and review nutrient cofactors, optimize protein intake (+add digestive enzymes and BHCL), ? add carnation, liposomal glutathione.
not sure about the rest.
thanks

[DrWoeller]

Lorraine,
It’s always possible to have some airborne mold affecting the lungs and sinuses, and not be growing in the gut, but I think that would be rare. Mold is likely not an issue here. Treating mild candida I feel is worthwhile, and if this individual is showing symptoms than most definitely.

Biocidin is an excellent way to go in this case.

1 – high testosterone? Is she being exposed to testosterone creams? Her DHEA is high too which could explain the high testosterone. Is she taking that as a supplement?
2 – Do a vitamin D test. High serotonin could be related to vitamin D deficiency as Vitamin D controls the gene regulating Tryptophan Hydroxylase 1 most active in
the gut. Low vitamin D can lead to high gut produced serotonin leading to inflammation, but low production of serotonin in the brain.

I think the addition of digestive enzymes and protein (amino acids) is a good idea. Because of elevated fatty acid metabolites L-carnitine at 1000mg daily is wortwhile. Glutathione would be okay too.

I would also consider adding some amino acids. New Beginnings has Amino Replete which works well to help support the neuro pathways.

I hope this helps.
Dr. Woeller

[Author]

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