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H.Pylori virulence factor

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    • November 10, 2016 at 2:37 pm #624
      Katey Greene

        I have a 45 year old client who was diagnosed in 2008 with crohn’s disease. She has subsequently been diagnosed with H.Pylor, which she eradicated with a different practitioner. Last month her stool sample from DRG Laps GI Pathogens Plus showed the H.Pylori was lowered to a score of 22, but that the virulence factor cagA was high/positive 922. Can you explain why that marker jumped, when the H.Pylori itself is low to nonexistent?
        (also, Her tests from last July indicated normal levels of H.pylori and virulence factor cagA, but a high entamoeba histolytic count which she treated with another practitioner).

      • November 10, 2016 at 4:14 pm #625
        DrWoeller
        Keymaster

          Katey,
          I am not very familiar with this test. I would suggest calling the lab and getting an explanation of the lab finding. Perhaps there is a lag time in that marker for eventual negative results to occur. I am assuming the patient is asymptomatic.

          Also, how was the Entamoeba histolytica detected? Was it PCR?

          Dr. Woeller

          • November 10, 2016 at 5:02 pm #627
            Katey Greene

              It was detected via this same lab and stool test (GI Pathogens Plus). This is the first time I have heard for DRG Labs…

          • November 11, 2016 at 7:16 am #631
            DrWoeller
            Keymaster

              Katey,
              Okay. Do you know if the E. histolytica was detected by antigen detection or PCR analysis?
              Dr.Woeller

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